PUBLIKATIONEN/PUBLICATIONS

Institut für Biochemie I/Institute for Biochemistry I

Auswahl/Selection

2011

Koch, D., Spiwoks-Becker, I., Sabanov, V., Sinning, A., Dugladze, T., Stellmacher, A., Ahuja, R., Grimm, J., Schüler, S., Müller, A., Angenstein, F., Ahmed, T., Diesler, A., Moser, M., Tom Dieck, S., Spessert, R., Boeckers, T.M., Fässler, R., Hübner, C.A., Balschun, D., Gloveli, T., Kessels, M.M., Qualmann, B. (2011).
Proper synaptic vesicle formation and neuronal network activity critically rely on syndapin I. EMBO J. (in press)

Schwintzer, L., Koch, N., Ahuja, R., Grimm, J., Kessels, M.M., Qualmann, B. (2011).
The functions of the actin nucleator Cobl in cellular morphogenesis critically depend on syndapin I. EMBO J.,30, 303147-303159

Qualmann B, Koch D, Kessels MM (2011).
Let’s go bananas: Revisiting the endocytic BAR code. EMBO J., 30, 3501-3515 

Kessels, M.M., Schwintzer, L., Schlobinski, D., Qualmann, B. (2011).
Controlling actin cytoskeletal organization and dynamics during neuronal morphogenesis.
Eur. J. Cell Biol., 90, 926-933 

2010

Hallbauer, J., Kreusch, S., Klemm, A., Wolf, G., Rhode, H. (2010).
Long-term serum proteomes are quite similar under high- and low-flux hemodialysis treatment.Proteomics Clin. Appl., 4, 953-961

2009

Dharmalingam, E., Haeckel, A., Pinyol, R., Schwintzer, L., Koch, D., Kessels, M.M., Qualmann, B. (2009).
F-BAR proteins of the syndapin family shape the plasma membrane and are crucial for neuromorphogenesis.
J. Neurosci., 29, 13715-13727

Fricke, R., Gohl, C., Dharmalingam, E., Grevelhörster, A., Zahedi, B., Harden, N., Kessels, M.M., Qualmann, B., Bogdan, S. (2009).
Drosophila Cip4/Toca-1 Integrates Membrane Trafficking and Actin Dynamics through WASP and SCAR/WAVE.
Curr. Biol., 19, 1429-1437

Qualmann B., Kessels M.M. (2009).
New players in actin polymerization--WH2-domain-containing actin nucleators.
Trends Cell Biol., 19, 276-285.

Salvarezza, S.B., Deborde, S., Schreiner, R., Campagne, F., Kessels, M.M., Qualmann, B., Caceres, A., Kreitzer, G., Rodriguez-Boulan, E. (2009).
LIM kinase 1 and cofilin regulate actin filament population required for dynamin-dependent apical carrier fission from the trans-Golgi network.
Mol. Biol. Cell, 20, 438-451.

2008

Haeckel, A., Ahuja, R., Gundelfinger, E.D., Qualmann, B., Kessels, M.M. (2008).
The actin-binding protein Abp1 controls dendritic spine morphology and is important for spine head and synapse formation.
J. Neurosci., 28, 10031-10044.

Qualmann, B., Kessels, M.M. (2008).
Actin nucleation: putting the brakes on Arp2/3.
Curr. Biol., 18, R420-423.

Onabajo, O.O., Seeley, M.K., Kale, A., Qualmann, B., Kessels, M., Han, J., Tan, T.H., Song, W. (2008).
Actin-binding protein 1 regulates B cell receptor-mediated antigen processing and presentation in response to B cell receptor activation.
J. Immunol., 180, 6685-6689.

Kreusch, S., Schulze, M., Cumme, G.A., Ditze, G., Moore, T, Rhode, H. (2008).
Searching biomarker candidates in serum using multidimensional native chromatography. I. Enhanced separation method.
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 875, 567-572.

Baum, A., Pohl. M., Kreusch, S., Cumme, G.A., Ditze, G., Misselwitz, J., Kiehntopf, M., Udby, L., Meier-Hellmann, A., Rhode, H. (2008).
Serum Biomarker search in serum using multidimensional native chromatography - II Method evaluation with Alport Syndrome and Severe Inflammation.
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 876, 31-40.

Schurigt, U., Hummel, K.M., Petrow, P.K., Gajda, M., Stöckigt, R., Middel, P., Zwerina, J., Janik, T., Bernhardt, R., Schüler, S., Scharnweber, D., Beckmann, F., Saftig, P., Kollias, G., Schett, G., Wiederanders, B., Bräuer, R. (2008).
Cathepsin K deficiency partially inhibits, but does not prevent, bone destruction in human tumor necrosis factor-transgenic mice.
Arthritis Rheum. 58, 422-434.

Cumme, G.A., K,reusch, S., Nagel, M., Rhode, H. (2008).
Multidimensional chromatography: Validation and efficient fishing for biomarkers and fractions containing them using the VisualCockpit software package.
Proteomics, 8, 37-41.

2007

Ahuja R, Pinyol R, Reichenbach N, Custer L, Klingensmith J, Kessels MM, Qualmann B. (2007)
Cordon-bleu is an actin nucleation factor and controls neuronal morphology. Cell, 131, 337-350.

Pinyol, R., Haeckel, A., Ritter, A., Qualmann, B., Kessels, M.M. (2007).
Regulation of N-WASP and the Arp2/3 complex by Abp1 controls neuronal morphology.
PLoS ONE, 2, e400. doi:10.1371/journal.pone.0000400

Ruettger A, Schueler S, Mollenhauer JA, Wiederanders B. (2007)
Cathepsins B, K and L are regulated by a defined collagen type II peptide via activation of classical protein kinase C and p38 MAP kinase in articular chondrocytes.
J. Biol. Chem. 283, 1043-1051

Kramer, G., Paul, A., Kreusch, A., Schüler, S., Wiederanders, B. and Schilling, K. (2007)
Optimized folding and activation of recombinant procathepsin L and S produced in Escherichia coli.
Protein Expr. Purif. 54, 147-156

Tsareva, S. A., Moriggl, R., Corvinus, F. M., Wiederanders, B., Schütz, A., Kovacic, B. and Friedrich, K. (2007)
Signal transducer and activator of trascription 3 activation promotes invasive growth of colon carcinomas through matrix metalloproteinase induction.
Neoplasia 9, 279-291

Mitre, E., Schulze, M., Cumme, G. A., Rößler, F., Rausch, T. and Rhode, H. (2007)
Turbo-Mixing in microplates.
J. Biomol. Screening 12, 361-369

2006

Kessels, M.M., Qualmann, B. (2006)
Syndapin oligomers interconnect the machineries for endocytic vesicle formation and the actin cytoskeleton.
J. Biol. Chem., 281, 13285-13299.

Kessels, M.M., Dong, J., Leibig, W., Westermann, P., Qualmann, B. (2006) Complexes of syndapin II with dynamin II promote vesicle formation at the trans-Golgi network.
J. Cell Sci., 119, 1504-1516.

Augsten, M.; Pusch, R.; Biskup, C.; Rennert, K.; Wittig, U.; Beyer, K.; Blume, A., Wetzker, R., Friedrich, K. and Rubio, I. (2006)
Live-cell imaging of endogenous Ras-GTP illustrates predominant Ras activation at the plasma membrane.
EMBO Reports 7, 46-51

Horn, A., Kreusch, S., Bublitz, R., Hoppe, H., Cumme, G. A., Schulze, M., Moore, T., Ditze, G. and Rhode, H. (2006)
Multidimensional proteomics of human serum using parallel chromatography of native constituents and microplate technology, Proteomics, 6, 559-570

Bublitz, R., Kreusch, S., Ditze, G., Schulze, M., Cumme,G. A., Fischer, C., Winter, A., Hoppe, H. and Rhode, H. (2006)
Robust protein quantitation in chromatographic fractions using matrix-assisted laser desorption/ionization mass spectrometry of tryptic peptides. Proteomics, 6, 3909-3917

Schüler, S., Wenz, I., Wiederanders, B., Slickers, P. and Ehricht, R. (2006) An alternative method to amplify RNA without loss of signal conservation for expression analysis with a Proteinase DNA microarray in the ArrayTube format.
BMC Genomics 7, 144

Rüttger, A., Mollenhauer, J., Löser, R., Gütschow, M., and Wiederanders, B. (2006)
Microplate assay for quantitative determination of cathepsin activities in viable cells using derivatives of 4-methoxy-β-naphthylamide. BioTechniques 41, 469-473.

Rhode, H., Kreusch, S., Cumme, G. A., Baum, A., Pohl, M., Moore, T. and Meier-Hellmann, A. (2006)
Search for serum biomarkers using an approach based on native multidimesional fractionation. Shock 26, suppl 1, 1

Ruckrich, T., Brandenburg, J., Cansier, A., Muller, M., Stevanovic, S., Schilling, K., Wiederanders, B., Beck, A., Melms, A., Reich, M., Driessen, C. and Kalbacher, H. (2006) Specificity of human cathepsin S determined by processing of peptide substrates and MHC class II-associated invariant chain. Biolo. Chem. 387, 1503-1511.

Kaulmann G., Palm, G. J., Schilling, K., Hilgenfeld, R. and Wiederanders, B. (2006)
The crystal structure of a Cys25 -> Ala mutant of human procathepsin S elucidates enzyme-prosequence interactions.
Protein Sci. 15, 2619-2629.

2005

Braun, A., Pinyol, R., Dahlhaus, R., Koch, D., Fonarev, P., Grant, B.D., Kessels, M.M., Qualmann, B. (2005).
EHD proteins associate with syndapin I and II and such interactions play a crucial role in endosomal recycling.
Mol. Biol. Cell, 16, 3642-3658.

tom Dieck, S., Altrock, W.D., Kessels, M.M., Qualmann, B., Regus, H., Brauner, D, Fejtová, A., Bracko, O., Gundelfinger, E.D., Brandstätter, J.H. (2005).
Molecular dissection of the photoreceptor ribbon synapse: physical interaction of Bassoon and RIBEYE is essential for the assembly of a functional ribbon complex.
J. Cell Biol., 168, 825-836.

Sachse, A., Wagner, A., Keller, M., Wagner, O., Wetzel, W. D., Layher, F., Venbrocks, R. A., Hortschansky, P., Pietrasnzyk, M., Wiederanders, B., Hempel, H. J., Bossert, J., Horn, J., Schmuck, K. and Mollenhauer, J. (2005)
Osteointegration of hydroxyapatite-titanium implants coated with nonglycosylated recombinant human bone morphogenetic protein-2 (BMP-2) in aged sheep. Bone 37, 699-710

Schurigt, U., Stopfel, N., Hueckel, M., Pfirschke, C., Wiederanders, B. and Brauer, R. (2005)
Local expression of matrix metalloproteinases, cathepsins, and their inhibitors during the development of murine antigen-induced arthritis.
Arthr. Res. Ther. 7, R174-R188

Loser, R., Schilling, K., Dimmig, E. and Gutschow M. (2005)
Interaction of papain-like cysteine proteases with dipeptide-derived nitriles.
J. Med. Chem. 48 , 7688-7707

Fitzgerald, J. S., Tsareva, S. A., Poehlmann, T. G., Berod, L., Meissner, A., Corvinus, F. M., Wiederanders, B., Pfitzner, E., Markert, U. R. and Friedrich K. (2005) Leukemia inhibitory factor triggers activation of signal transducer and activator of transcription 3, proliferation, invasiveness, and altered protease expression in choriocarcinoma cells. International Journal of Biochem. Cell Biol. 37, 2284-2296.

Kreusch, S., Hoppe, H., Bublitz, R., Moore, T., Hallbauer, J. Schulze, M., Cumme, G.A., Misselwitz J., Klemm, A., and Rhode, H. (2005) Non-denaturating multidimensional separation of serum: Improved method, automatization, and applications.
Mol. Cell. Proteomics 4 S1, 211-S211

2004

Kessels, M.M., Qualmann, B. (2004).
The syndapin protein family - linking membrane trafficking with the cytoskeleton.
J. Cell Sci., 117, 3077-3086.

Qualmann, B., Boeckers T.B., Jeromin, M., Gundelfinger, E. D., Kessels, M.M. (2004).
Linkage of the actin cytoskeleton to the postsynaptic density via interactions of Abp1 with ProSAP/Shanks.
J. Neurosci., 24, 2481-2495.

Merrifield, C.J., Qualmann, B., Kessels, M.M., Almers, W. (2004).
Neural Wiskott Aldrich Syndrome Protein (N-WASP) and the Arp2/3 complex are recruited to sites of clathrin-mediated endocytosis in cultured fibroblasts.
Eur. J. Cell Biol., 83, 13-18.

Rhode, H., Schulze, M., Renard, S., Zimmermann, P., Moore, T, Cumme, G. A. and Horn, A. (2004).
An improved method for checking HTS/uHTS liquid-handling systems. J. Biomol. Screening 9, 726-733.